Genetics is the study of genes, genetic variation, and heredity in living organisms. A gene is the basic physical and functional unit of heredity. Genes, which are made up of DNA, act as instructions to make molecules called proteins.
The Human Genome Project has estimated that humans have 20,000 - 25,000 genes. Every person has two copies of each gene, one inherited from each parent. Most genes are the same in all people, but less than 1% of genes are slightly different between people. Poplar tree genome suggests more than 45,000 genes.
Vitamin C, or L-ascorbic acid, or ascorbate, is an essential nutrient for humans, a water-soluble vitamin. Humans, unlike most animals, are unable to synthesize vitamin C, so it is an essential dietary component.
Vitamin C is required for the biosynthesis of collagen (an essential component of connective tissue), L-carnitine, and certain neurotransmitters, it is also involved in protein metabolism.
Vitamin C is also an important physiological antioxidant and has been shown to regenerate other antioxidants within the body, including alpha-tocopherol (vitamin E). Vitamin C regenerates vitamin E by reducing vitamin E radicals formed when vitamin E scavenges the oxygen radicals.
Vitamin C plays an important role in immune function and improves the absorption of nonheme iron, the form of iron present in plant-based foods.
Approximately 70%–90% of vitamin C is absorbed at moderate intakes of 30–180 mg a day. At doses above 1 g a day, absorption falls to less than 50% and absorbed, unmetabolized ascorbic acid is excreted in the urine.
Insufficient vitamin C intake causes scurvy, which is characterized by fatigue or lassitude, connective tissue weakness, and capillary fragility.
Cells accumulate vitamin C. The total body content of vitamin C ranges from 300 mg (at near scurvy) to about 2 g.
High levels of vitamin C are maintained in cells and tissues, and are highest in leukocytes (white blood cells), eyes, adrenal glands, pituitary gland, and brain.
Relatively low levels of vitamin C are found in extracellular fluids, such as plasma, red blood cells, and saliva.