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mineral

  • All Known Essential Minerals

    Minerals (nutrients) are inorganic substances (contain no carbon) that are necessary for normal body function and development.

    Macrominerals

    Macro-minerals are needed in large doses (approximate recommended daily intake, milligrams (mg) per day ): 

    1. potassium, K (3500 mg) - metal, ions are necessary for the function of all living cells; 
    2. chloride, Cl− (3400 mg) - essential electrolyte in all body fluids; 
    3. sodium, Na, natrium (2400 mg) - metal, essential for all animals and some plants;
    4. calcium, Ca (1000 mg) - metal, essential for living organisms, produced in supernova nucleosynthesis;
    5. phosphorus, P (1000 mg) - in the form of the phosphate is required for all known forms of life; 
    6. choline (425 - 550 mg) - essential vitamin-like (vitamin B4) nutrient, synthesized in human body, but not sufficiently;
    7. magnesium, Mg (350 mg) - metal, essential for all known living organisms;

    Trace Minerals

    Trace minerals are needed in very small amounts (recommended daily intake, milligrams (mg) or micrograms (mcg) per day: 

    1. iron, Fe (15 mg) - metal, found in nearly all living organisms;
    2. zinc, Zn (8 - 11 mg) - metal, essential for humans and other organisms;
    3. manganese, Mn (5 mg) - metal, toxic essential trace element;
    4. fluorineF, fluoride ion, F− (3 - 4 mg) - a beneficial poisonous element, essential for bone solidity;
    5. copper, Cu (2 mg) - metal, essential to all living organisms;
    6. iodine, I (150 mcg) - a key component of thyroid hormones;
    7. selenium, Se (35mcg) - toxic in large doses, essential micronutrient for animals;
    8. chromium, Cr (30 mcg) - chromium (III) is questionably essential for humans.

  • Zinc

    Zinc is a nutritionally essential mineral needed for catalytic, structural, and regulatory functions in the body.

    The RDA (recommended daily allowance) for adult women and men is 8 mg a day and 11 mg a day of zinc, respectively.

    Severe zinc deficiency is a rare, genetic or acquired condition. Dietary zinc deficiency, often called marginal zinc deficiency, is quite common in the developing world, affecting an estimated 2 billion people. Zinc deficiency can cause impaired growth and development in children, pregnancy complications, immune dysfunction, and increased susceptibility to infections. Long-term consumption of zinc in excess of the tolerable upper intake level of 40 mg a day for adults can result incopper deficiency.

    Zinc bioavailability is relatively high in meat, eggs, and seafood. Zinc is less bioavailable from whole grains and legumes due to the inhibitory effects of phytic acid on absorption of the mineral.

Einstein:

Not everything that can be counted counts, and not everything that counts can be counted.

Protein Digestibility-Corrected Amino Acid Score

The protein digestibility-corrected amino acid score (PDCAAS) has been adopted by FAO/WHO as the preferred method for the measurement of the protein value in human nutrition. 

PDCAAS = Amino Acid Score x Digestibility

The method is based on comparison of the concentration of the first limiting essential amino acid in the test protein with the concentration of that amino acid in a reference (scoring) pattern. This scoring pattern is derived from the essential amino acid requirements of the preschool-age child.

Although the principle of the PDCAAS method has been widely accepted, critical questions have been raised in the scientific community:

  1. the validity of the preschool-age child amino acid requirement values (more than 4 times greater than the EAA requirement for an adult),
  2. the validity of correction for fecal instead of ileal digestibility,
  3. the truncation of PDCAAS values to 100%.

The reference scoring pattern was based on studies performed more than 25 years ago on a limited number of 2-year-old children recovering from malnutrition.

According to the current official recommendations, a 2-year old child needs ~ 3x higher essential-to-non-essential amino acid ratio, and needs essential amino acids in different proportions than adult. Methionine/cysteine is the limiting essential amino acids for adults, and for children it is lysine or tryptophan.

The use of fecal digestibility overestimates the nutritional value of a protein because amino acid nitrogen entering the colon is lost for protein synthesis in the body and is, at least in part, excreted in urine as ammonia.

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