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lysine

  • Protein Quality of Cereal-Based Diets

    Protein quantity plant-based diets is shown not to be an issue. Inadequate amino acid supply is not an issue with most cereal-based diets.

    When used to score plant-based diets in India, no marked deficiencies are identified. All regions score > 1 for adults, whilst for children scores range from > 1, (Tamil Nadhu) from 6 months of age to 0.78 (West Bengal), rising to 0.9 in the 2-5 year old, consistent with reports that high-lysine maize supports similar weight and height growth to that of casein. 

    Digestibility is identified as a problem for some cereals (millet (Panicum miliaceum) and sorghum (Sorghum sp.)) and generally is poorly understood.

    A new maintenance requirement pattern is developed, with higher values than those of Food and Agriculture Organization / World Health Organization / United Nations University (1985) but lower values than the Massachusetts Institute of Technology pattern (Young et al. 1989).

    Calculations of age-related amino acid requirements are based on most recent estimates of human growth and maintenance protein requirements, a tissue amino acid pattern and the new maintenance amino acid pattern. These values appear valid when used to score plant proteins, since they indicate values similar to or less than the biological value measured directly in young children.

  • EAR and RDA for Amino Acids

    Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) for amino acids (protein) for healthy adults 19 y and older, mg/kg/day:

    • Estimated Average Requirement (EAR): average, estimated to meet the requirements of 50%.
    • Recommended Dietary Allowance (RDA): average, sufficient to meet the nutrient requirements of nearly all.
    Amino Acids EAR RDA
    phenylalanine + tyrosine 27 33
    valine 19 24
    threonine 16 20
    tryptophan 4 5
    methionine + cysteine 15 19
    leucine 34 42
    isoleucine 15 19
    lysine 31 38
    histidine 11 14
  • Amino Acid Requirements for Adults

    Estimates of Amino Acid Requirements for adultsmg / kg per day

    • Phenylalanine + tyrosine: 14
    • Leucine: 14
    • Methionine + cystine13
    • Histidine: 8–12
    • Lysine: 12
    • Isoleucine: 10
    • Valine: 10
    • Threonine: 7
    • Tryptophan: 3.5

  • All Essential Amino Acids

    An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized by the organism, and must be supplied in diet. 

    The 9 amino acids humans cannot synthesize (F V T W M L I K H):

    • phenylalanine
    • valine
    • threonine
    • tryptophan
    • methionine
    • leucine
    • isoleucine
    • lysine
    • histidine

    Animal and plant proteins are made up of about 20 common amino acids.

    Synthesis of 6 other amino acids - conditionally essential - can be limited under special conditions (R C G Q P Y)arginine, cysteine, glycine, glutamine, proline, and tyrosine.

    Dispensable amino acids can be synthesized in the human body, 5 (A D N E S): alanine, aspartic acid, asparagine, glutamic acid and serine .

John Stuart Mill

A person may cause evil to others not only by his actions but by his inaction, and in either case he is justly accountable to them for the injury.

Zinc

Zinc is a nutritionally essential mineral needed for catalytic, structural, and regulatory functions in the body.

The RDA (recommended daily allowance) for adult women and men is 8 mg a day and 11 mg a day of zinc, respectively.

Severe zinc deficiency is a rare, genetic or acquired condition. Dietary zinc deficiency, often called marginal zinc deficiency, is quite common in the developing world, affecting an estimated 2 billion people. Zinc deficiency can cause impaired growth and development in children, pregnancy complications, immune dysfunction, and increased susceptibility to infections. Long-term consumption of zinc in excess of the tolerable upper intake level of 40 mg a day for adults can result in copper deficiency.

Zinc bioavailability is relatively high in meat, eggs, and seafood. Zinc is less bioavailable from whole grains and legumes due to the inhibitory effects of phytic acid on absorption of the mineral.

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