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Short knowledge summaries, facts and citations, related to fruitarianism from scientific internet publications, mass media and other seemingly credible online sources, with links

In 1991, approximately 200 studies that examined the relationship between fruit and vegetable intake and cancers of the lung, colon, breast, cervix, esophagus, oral cavity, stomach, bladder, pancreas, and ovary are reviewed.

A statistically significant protective effect of fruit and vegetable consumption was found in 128 of 156 dietary studies. For most cancer sites, persons with low fruit and vegetable intake (at least the lower one‐fourth of the population) experience about twice the risk of cancer compared with those with high intake, even after control for potentially confounding factors.

For lung cancer, significant protection was found in 24 of 25 studies after control for smoking in most instances. Fruits, in particular, were significantly protective in cancers of the esophagus, oral cavity, and larynx, for which 28 of 29 studies were significant. Strong evidence of a protective effect of fruit and vegetable consumption was seen in cancers of the pancreas and stomach (26 of 30 studies), as well as in colorectal and bladder cancers (23 of 38 studies). For cancers of the cervix, ovary, and endometrium, a significant protective effect was shown in 11 of 13 studies, and for breast cancer a protective effect was found to be strong and consistent in a meta analysis.

It would appear that major public health benefits could be achieved by substantially increasing consumption of these foods.

A new study tested the psychological benefits of a two-week clinical intervention to increase fruit and vegetable consumption in 171 young adults (aged 18–25).

Participants were randomly assigned into

  1. a diet-as-usual control condition,
  2. an ecological momentary intervention (EMI) condition involving text message reminders to increase their consumption plus a voucher to purchase fruits and vegetables,
  3. or a fruit and vegetable intervention (FVI) condition in which participants were given two additional daily servings of fresh fruits and vegetables to consume on top of their normal diet.

Only participants in the last group (FVI) condition showed improvements to their psychological well-being with increases in vitality, flourishing, and motivation relative to the other groups. No changes were found for depressive symptoms, anxiety, or mood.

Giving young adults fresh fruit and vegetables to eat can have psychological benefits even over a brief period of time.

Thermic effect of food (TEF) is the amount of energy expenditure above the resting metabolic rate due to the cost of processing food for use and storage. The effect varies substantially for different food components. The mechanism is unknown.

A commonly used estimate of the thermic effect of food is about 10% of one's caloric intake. 

The primary determinants of daily thermic effect are: 

  1. the total caloric content of the meals,
  2. the macronutrient composition of the meals ingested.

Macronutrients:

The thermic effect of food is the energy required for digestion, absorption, and disposal of ingested nutrients, and depends on the composition of the food consumed:

  • Protein: 20-35 % of the energy consumed,
  • Carbohydrates and fats5-15 %.

Meal frequency has little to no thermic effect. 

Insulin

Thermic effect also depends on the insulin sensitivity of the individual, with more insulin-sensitive individuals having a significant effect while individuals with increasing resistance have negligible to zero effects. Both insulin resistance and obesity are independently associated with impaired thermic effect of food at rest, but "the responsiveness of thermogenesis to exercise before a meal is related to the obese state and not independently to insulin resistance per se."

Exercise

The thermic effect of food is marginally increased by 7-8 calories per hour with exercise:

  • aerobic training of sufficient duration and intensity
  • and by anaerobic weight training.

"Negative"  Caloric Balance

Celery, grapefruit, lemon, lime, apple, lettuce, broccoli, and cabbage are often claimed to have negative caloric balance, requiring more energy to digest than recovered from the food. There is no scientific evidence to show that any of these foods have a negative caloric impact.

Modern diets are largely heat-processed and as a result contain high levels of advanced glycation end products (AGEs), also known as glycotoxins. Dietary advanced glycation end products (dAGEs) are known to contribute to increased oxidant stress and inflammation, which are linked to the recent epidemics of diabetes and cardiovascular disease.

Dry heat promotes new dAGE formation by 10-100 times above the uncooked state across food categories. Animal-derived foods that are high in fat and protein are generally rich in glycotoxins and prone to formation of new glycotoxins during cooking. Carbohydrate-rich foods such as vegetables, fruits, whole grains (but also milk) contain relatively few glycotoxins, even after cooking.

The formation of new glycotoxins during cooking was: 

  • prevented by the AGE inhibitory compound aminoguanidine
  • and significantly reduced by
    • cooking with moist heat,
    • using shorter cooking times,
    • cooking at lower temperatures,
    • and by use of acidic ingredients (such as lemon juice or vinegar).

Advanced glycation end products (AGEs), are a diverse group of highly oxidant compounds with pathogenic significance in diabetes and in several other chronic diseases. Glycotoxins are created through a Maillard or browning reaction - it is a part of normal metabolism, but if excessively high levels of glycotoxins are reached in tissues and the circulation they can become pathogenic, which is related to their ability to promote oxidative stress and inflammation by binding with cell surface receptors or cross-linking with body proteins, altering their structure and function.

Glycotoxins also exist in foods: they are naturally present in uncooked animal-derived foods, and cooking results in the formation of new AGEs: grilling, broiling, roasting, searing, and frying propagate and accelerate new AGE formation. Recent studies clearly show that dAGEs are absorbed and contribute significantly to the body’s AGE pool.

Avoidance of dAGEs, glycotoxins in food, helps delay chronic diseases and aging in animals and possibly in human beings.

Glycotoxins in the diet represent pathogenic compounds that have been linked to the induction and progression of many chronic diseases. High temperature and low moisture consistently and strongly drive their formation in foods. Comparatively brief heating time, low temperatures, high moisture, and/or pre-exposure to an acidified environment are effective strategies to limit new formation in food.

A significantly reduced intake of dAGEs can be achieved by reducing intake of solid fats, fatty meats, full-fat dairy products, and highly processed foods, and by increasing the consumption of legumes, vegetables, fruits, and whole grains. 

Low-AGE–generating cooking methods are 

  • poaching,
  • steaming,
  • stewing, 
  • boiling.

For example, the high AGE content of broiled chicken (5,828 kU/100 g) can be significantly reduced to 1,124 kU/100 g when the same piece of meat is either boiled or stewed. 

Future studies should continue to investigate the health effects of AGEs and refine recommendations for safe dietary intakes. However, current data support the need for a paradigm shift that acknowledges that how we prepare and process food may be equally important as nutrient composition.

Among Chinese adults, a higher level of fruit consumption was associated with lower blood pressure and blood glucose levels and, largely independent of these and other dietary and nondietary factors, with significantly lower risks of major cardiovascular diseases

Aggregated definitions of terms used on Fruitarian's Network. A definition is a statement of the meaning of a term - a word, a phrase, or a set of other symbols.

Relevant quotes - statements and thoughts relevant to fruitarianism by various people.

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Pythagoras

As long as Man continues to be the ruthless destroyer of lower living beings, he will never know health or peace.

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