In man, physiological amounts of vitamin are absorbed by the intrinsic factor mediated mechanism exclusively in the ileum, the third portion of the small intestine. Human faeces contain appreciable quantities of vitamin B12 or vitamin B12-like material presumably produced by bacteria in the colon, but this is unavailable to the non-coprophagic individual. However, the human small intestine also often harbours a considerable microflora and this is even more extensive in apparently healthy southern Indian subjects. We now show that at least two groups of organisms in the small bowel, Pseudomonas and Klebsiella sp., may synthesise significant amounts of the vitamin.
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B12 May Be Synthesized by Small Intestine Microflora
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Grains are small, hard, dry seeds, with or without attached hulls or fruit layers, harvested for human or animal consumption. The two main types of commercial grain crops are cereals (e.g. wheat, rye) and legumes (e.g. beans, soybeans). Seeds
After being harvested, dry grains are more durable than other staple foods, such as starchy fruits (e.g. plantains, breadfruit) and tubers (e.g. sweet potatoes, cassava). This durability has made grains well suited to industrial agriculture, since they can be mechanically harvested, transported, stored for long periods, and milled for flour or pressed for oil. Major global commodity markets exist for canola, maize, rice, soybeans, wheat, and other grains but not for tubers, vegetables, or other crops.