There is no good evidence of any adverse medical effects associated with the consumption of water with fluoride naturally or artificially added at a concentration of 0.5 – 1.0 mg / litre other than the increase in dental fluorosis. US studies in areas with natural fluoride levels of up to 8 mg / litre found no clinical evidence of harm. However there is clear evidence from India and China that skeletal fluorosis and an increased risk of bone fractures occur as a result of long-term excessive exposure to fluoride (total intakes of 14 mg fluoride per day), and evidence suggestive of an increased risk of bone effects at total intakes above about 6 mg fluoride per day.
All about fruitarianism with a long-term fruitarian, Lena
Fluoride in Water and Dental or Skeletal Fluorosis
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The thinking man must oppose all cruel customs no matter how deeply rooted in tradition and surrounded by a halo. When we have a choice, we must avoid bringing torment and injury into the life of another, even the lowliest creature; to do so is to renounce our manhood and shoulder a guilt which nothing justifies.
Vitamin C, or L-ascorbic acid, or ascorbate, is an essential nutrient for humans, a water-soluble vitamin. Humans, unlike most animals, are unable to synthesize vitamin C, so it is an essential dietary component.
- Vitamin C is required for the biosynthesis of collagen (an essential component of connective tissue), L-carnitine, and certain neurotransmitters, it is also involved in protein metabolism.
- Vitamin C is also an important physiological antioxidant and has been shown to regenerate other antioxidants within the body, including alpha-tocopherol (vitamin E). Vitamin C regenerates vitamin E by reducing vitamin E radicals formed when vitamin E scavenges the oxygen radicals.
- Vitamin C plays an important role in immune function and improves the absorption of nonheme iron, the form of iron present in plant-based foods.
Approximately 70%–90% of vitamin C is absorbed at moderate intakes of 30–180 mg a day. At doses above 1 g a day, absorption falls to less than 50% and absorbed, unmetabolized ascorbic acid is excreted in the urine.
Insufficient vitamin C intake causes scurvy, which is characterized by fatigue or lassitude, connective tissue weakness, and capillary fragility.
Cells accumulate vitamin C. The total body content of vitamin C ranges from 300 mg (at near scurvy) to about 2 g.
- High levels of vitamin C are maintained in cells and tissues, and are highest in leukocytes (white blood cells), eyes, adrenal glands, pituitary gland, and brain.
- Relatively low levels of vitamin C are found in extracellular fluids, such as plasma, red blood cells, and saliva.